TONIGHT: Lester Holt interviews Dr. Anthony Fauci as the US adds travel restrictions in response to the Omicron Covid-19 variant. We'll have the latest tonight on NBC Nightly News at 6:30 ET / 5:30 CT (check your local NBC station listings). Read more: https://nbcnews.to/3p4LxV5 | NBC Nightly News with Tom Llamas

"One pill could kill. One pill, one time, game over." Tonight on NBC Nightly News, Lester Holt talks to Cheri Oz, Special Agent in Charge of the DEA's Phoenix Field Division, about the fentanyl crisis. Watch the full report at 6:30 pm ET / 5:30 pm CT (check local listings). | NBC Nightly News with Tom Llamas

Coming up – Our series 'The Fleecing of America' returns. Lester Holt interviews the chair of the Pandemic Response Accountability Committee The Academy condemned Will Smith for slapping Chris Rock at the Oscars. We have reporting from Miguel Almaguer. And more on NBC Nightly News at 6:30 ET / 5:30 CT (check local listings). | NBC Nightly News with Tom Llamas