Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Inherited mutations in DNA damage gene repair (gDDR) in Italian men with metastatic prostate cancer. Use of a navigable interface for integrated whole genome and transcriptome sequencing as a platform ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Transcription Factors (TFs) are pivotal regulators of gene expression and have been implicated in a variety of diseases, including cancer, neurological disorders, autoimmune conditions, and metabolic ...

Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like ...

Transcription factors are a class of proteins that interact with DNA to regulate gene expression. They’re also implicated in many cancers. For years, scientists have considered transcription factors ...

Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...