Hydrogen exchange experiments monitored by NMR and mass spectrometry reveal that the amyloidogenic D67H mutation in human lysozyme significantly reduces the stability of the β-domain and the adjacent ...
Lysozyme is abundant in secretions such as saliva, human milk, tears and mucus, and is also known as N-acetylmuramide glycanhydrolase or muramidase. It is an antimicrobial enzyme that is generated by ...
An instrument which combines Raman spectroscopy with dynamic light scattering (DLS) can be used to study lysozyme’s unfolding and refolding processes under thermal stress conditions. Through the ...
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