The folding of α-helical integral membrane proteins has been postulated to follow a two-stage path, involving (i) the formation of individually stable α-helices and (ii) their association giving rise ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 35 (August 31, 2021), pp. 1-2 (2 pages) R. M. Voorhees, I. S. Fernandez ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

Membrane proteins do not reveal their structures easily. Because they are particularly hard to crystallize, such proteins make X-ray crystallography expensive and time-consuming. So, many ...

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place. This membrane protects the cell from its surroundings and divides it into ...

A research team co-led by scientists from Kyoto University Institute for Integrated Cell-Material Sciences (iCeMS) in Japan has uncovered mechanisms of how dying cells activate a protein that triggers ...