Figure 1: Cross-coupling reactions using configurationally stable, optically active secondary alkyl nucleophiles. Internal coordination of the nitrogen atom in the azastannatrane backbone was proposed ...

Making carbon–carbon bonds is hard. Linking racemic mixtures of two alkyls while simultaneously controlling the stereochemistry of both ends of the product is nigh on impossible. Now Gregory Fu, ...

The molecules in question are known as "nucleophiles" (literally, nucleus lovers), which share their electrons with "electrophiles" (literally, electron lovers) and serve as their atomic dance ...

Chemists are amped up about two new reactions that use electricity to form different types of carbon-carbon bonds. One transformation builds sp 3-sp 3 C–C bonds and the other creates sp 2-sp 3 C–C ...

Bifunctional acid−base catalysts are highly desirable for industrially relevant chemical processes. Owing to their ability to activate electrophiles and nucleophiles simultaneously, they allow the ...