Homologous recombination (HR) is a universal DNA repair mechanism that faithfully restores genomic integrity following double-strand breaks (DSBs) in DNA. The details concerning the transfer of ...

HOUSTON -- (Oct. 7, 2011) – In children with genomic disorders, often a gamete – egg or sperm – has gone disastrously awry with either a duplication or deletion of genetic material that results in ...

Ectopic recombination between repeated but nonallelic DNA sequences plays a major role in genome evolution, creating gene families and generating copy number variation and pathological rearrangements ...

One of the most striking patterns of genome structure is the tight, typically negative, association between transposable elements (TEs) and meiotic recombination rates. While this is a highly ...